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KMID : 0364019910240010098
Korean Journal of Thoracic and Cardiovascular Surgery
1991 Volume.24 No. 1 p.98 ~ p.105
Secondary Primary Lung Carcinoma after Total Laryngectomy Due to Laryngeal Carcinoma





Abstract
There have been reports concerning the association of laryngeal carcinoma and lung cancer. Second primary respiratory tract malignancies occcur frequently in patients who have undergone the treatment of laryngeal cancer probably because they are exposed to the same carcinogen.
Recently, we have experienced two patients who developed second primary lung cancer 30 and 41 months after the first diagnosis of laryngeal cancer at the Department of Thoracic & Cardiovascular Surgery Yonseei University College of Medicine. Relative long interval between the two carcinomas indicated metastasis unlikely.
From a therapeutic standpoint, it is of great importance that they should be regarded as separate primaries and not as metastasis. Longevity will depends on a presumption that the lesions are separate primaries and the status of stage at the time of detection of second primary lesion.
The follow-up of patients who are seen with carcinomas of the head and neck should be done at regular interval and include a chest roentgenogram and cytologic examination of sputum to detect early changes before the tumors becomes incurable.
The first 76 year old patient with left upper lobectomy due to the T2NOMO lung cancer has been in good condition to present. But the second 55 year old patient with right pneumonectomy due to the T2NOMO lung cancer died of respiratory failure and septic pneumonia 3 months after operation and chemotherapy.
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